Cercanías C-1 (from T4 only): direct to Chamartín, Nuevos Ministerios and Atocha in ~25 minutes, ~€2.60, trains every 30 minutes — the calm choice with luggage if you land at T4 and sleep near Sol/Huertas/Lavapiés (Atocha end). Metro L8 (all terminals): 12 minutes to Nuevos Ministerios, then transfer; €3 airport supplement on top of the fare; fastest to Chamberí/Salamanca. Exprés bus: 24 hours a day, €5, ~40 minutes to Cibeles (stops at O’Donnell and Atocha by day) — the night-arrival default and the Gran Vía choice. Taxi: flat €33 to anywhere inside the M-30, ~25–35 minutes; VTC apps usually a few euros less.
Landing T4 + staying near Atocha/Sol → Cercanías. Landing T1–T3 → bus or metro (the C-1 doesn’t serve those terminals without the airport shuttle). Arriving 00:00–06:00 → Exprés bus or taxi, no exceptions — the rails sleep. Party of three with bags → the €33 taxi beats everything per head. And buy the Multi card at the airport machine regardless; you’ll use it all week.
Curated picks are coming — meanwhile, the live search covers every bookable property at the same price or better.